
Understanding the Risk
If you’re a young woman diagnosed with breast cancer and carry a BRCA1 or BRCA2 mutation, you’re at a higher risk not just for a second breast cancer—but also ovarian cancer. But here’s the good news: science now confirms that certain preventive surgeries can significantly improve survival.
A large international study (published in The Lancet Oncology, 2025) tracked over 5,000 women under age 40 with BRCA mutations and breast cancer—and the results were clear.
What Are Risk-Reducing Surgeries?


1. Risk-Reducing Mastectomy (RRM):
Removal of the healthy breast to prevent second breast cancers.
2. Risk-Reducing Salpingo-Oophorectomy (RRSO):
Removal of the ovaries and fallopian tubes to prevent ovarian cancer.
What This Means for You
If you’re a BRCA1/2 mutation carrier and have been diagnosed with breast cancer at a young age:
• Risk-reducing mastectomy helps prevent new breast cancers and extends survival.
• Ovarian removal (RRSO) significantly improves overall survival—especially for BRCA1 carriers and those with HER2-positive breast cancer.
Final Thoughts
This study reinforces the power of preventive surgery when tailored to your unique risk profile. These aren’t just life-saving—they’re life-extending.
Consult Dr. Saadvik Raghuram to understand your BRCA risk and treatment options
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